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Localized hypoplasia of dental enamel
- ... dental problems, such as missing teeth, irregular tooth enamel, and crowded teeth.Many individuals with Apert syndrome have vision problems due to eye abnormalities, which can include bulging eyes (exophthalmos), wide-set ...
- ... protein can lead to severe problems with developing enamel or cause milder defects such as shallow pits or horizontal grooves in the teeth.In the autosomal recessive form of amelogenesis imperfecta, ...