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Familial sick sinus syndrome
- ... loss-of-function mechanisms contribute to SCN5A-related familial sick sinus syndrome. PLoS One. 2010 Jun 7;5(6):e10985. ...
- ... with no history of the disorder in their family.When sick sinus syndrome results from mutations in the HCN4 gene, it ... R, Baruscotti M, Gnecchi-Ruscone T, DiFrancesco D. Familial sinus bradycardia associated ... 8;354(23):2520. Citation on PubMed
- ... been associated with an increased risk of developing sick sinus syndrome. This condition affects the function of the sino- ... their sample who had the Arg721Trp variation developed sick sinus syndrome during their lifetime, compared with about 6 percent ...
- ... HCN4 gene have been identified in people with sick sinus syndrome, a heart condition that affects the function of ...