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Familial myelofibrosis
- Primary myelofibrosis is a condition characterized by the buildup of scar tissue (fibrosis) in the bone marrow, the tissue that produces blood cells. Because ...
- ... When it is inherited, the condition is called familial essential thrombocythemia. ... Bordessoule D, Le Bousse-Kerdiles MC, Vainchenker W, Giraudier S. New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G1/ ...
- ... with no history of the condition in their families. Chromosomal rearrangements that lead to a PDGFRB fusion ...
- ... have been identified in some people with primary myelofibrosis. This condition is characterized by scar tissue (fibrosis) ... that produces blood cells.Like essential thrombocythemia, primary myelofibrosis is associated with the MPL gene mutations referred ...
- ... in the TET2 gene are associated with primary myelofibrosis. This condition is characterized by scar tissue (fibrosis) ... gene mutations play in the development of primary myelofibrosis. More About This Health Condition MedlinePlus Genetics provides ...
- ... criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Curr Hematol Malig Rep. 2009 Jan;4(1): ...