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Severe hemophilia B
- ... be difficult to control. The variants that cause severe hemophilia almost completely eliminate the activity of coagulation factor ... hemophilia is unknown. F8 F9 Hemophilia A and hemophilia B are inherited in an X-linked recessive pattern. ...
- ... reproductive tract bleeding during pregnancy and childbirth. In severe cases of von Willebrand disease, heavy bleeding occurs ... of affected individuals, and is usually the most severe. Another form of the disorder, acquired von Willebrand ...