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Results 1 - 10 of 131 for Lack of T cell function
  1. Activated PI3K-delta syndrome 
    ... infections and that die earlier than usual. The lack of functioning B cells ... immune system function may contribute to the development of lymphoma in ...
    https://medlineplus.gov/.../condition/activated-pi3k-delta-syndrome - Genetics
  2. DOCK8 immunodeficiency syndrome 
    ... this protein impairs normal immune cell development and function. It is thought that ... syndrome. A lack of DOCK8 protein also impairs B cell maturation ...
    https://medlineplus.gov/.../dock8-immunodeficiency-syndrome - Genetics
  3. Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome 
    ... Levings MK, Roncarolo MG. Defective regulatory and effector T cell functions in patients with FOXP3 mutations. J Clin Invest. ... X-linked: forkhead box protein 3 mutations and lack of regulatory T cells. J Allergy Clin Immunol. 2007 Oct;120(4): ...
    https://medlineplus.gov/...ocrinopathy-enteropathy-x-linked-syndrome - Genetics
  4. Purine nucleoside phosphorylase deficiency 
    ... for destruction. The most severely affected individuals, who lack T cells and B cells, have a serious condition called ...
    https://medlineplus.gov/...urine-nucleoside-phosphorylase-deficiency - Genetics
  5. ZAP70-related severe combined immunodeficiency 
    ... T cells. These include cytotoxic T cells (CD8+ T cells), whose functions include destroying cells infected by viruses. The ZAP70 ... in the activation of helper T cells (CD4+ T cells). These cells direct and assist the functions of the immune system by influencing the activities ...
    https://medlineplus.gov/...-related-severe-combined-immunodeficiency - Genetics
  6. X-linked hyper IgM syndrome 
    ... Slater JE, Nelson DL, Strober W. Defects of T-cell effector function and post-thymic maturation in X-linked hyper-IgM syndrome. J Clin Invest. 1999 Apr;103(8):1151-8. doi: 10.1172/JCI5891. ... Levy J, Espanol-Boren T, Thomas C, Fischer A, Tovo P, Bordigoni P, ...
    https://medlineplus.gov/.../condition/x-linked-hyper-igm-syndrome - Genetics
  7. CLN5 disease 
    ... K, Scifo E, Tyynela J, Jalanko A, Braulke T. Cell biology and function of neuronal ceroid lipofuscinosis-related proteins. Biochim Biophys ...
    https://medlineplus.gov/genetics/condition/cln5-disease - Genetics
  8. Atopic dermatitis 
    ... signaling, and as a result, certain lymphocytes called T cells do not develop or function properly. The number of these cells is normal, but their response to foreign invaders such as bacteria and fungi is diminished. The T cell abnormalities lead to a weakened immune system ...
    https://medlineplus.gov/genetics/condition/atopic-dermatitis - Genetics
  9. FBXL4-related encephalomyopathic mitochondrial DNA depletion syndrome 
    ... syndrome lead to a loss of FBXL4 protein function. A lack of this protein's activity leads to problems with the maintenance of mtDNA, which can reduce the amount of mtDNA in cells (known as mtDNA depletion). Depletion of mtDNA impairs mitochondrial function in many of the body's cells and ...
    https://medlineplus.gov/...thic-mitochondrial-dna-depletion-syndrome - Genetics
  10. Netherton syndrome 
    ... is unable to control serine peptidase activity. The lack of LEKT1 function allows the serine peptidases to be abnormally active ...
    https://medlineplus.gov/genetics/condition/netherton-syndrome - Genetics
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