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Familial myelofibrosis
- Primary myelofibrosis is a condition characterized by the buildup of scar tissue (fibrosis) in the bone marrow, the tissue that produces blood cells. Because ...
- ... When it is inherited, the condition is called familial essential thrombocythemia. ... Bordessoule D, Le Bousse-Kerdiles MC, Vainchenker W, Giraudier S. New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G1/ ...
- ... with no history of the condition in their families. Chromosomal rearrangements that lead to a PDGFRB fusion ...
- ... criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Curr Hematol Malig Rep. 2009 Jan;4(1): ...