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Decreased mitochondrial number
- ... the production of mitochondrial proteins can also disrupt mitochondrial energy production.Although the exact mechanism is unclear, researchers believe that impaired oxidative phosphorylation can lead to cell death because of decreased energy available in the cell. Certain tissues that ...
- ... common. Additionally, people with this condition may have decreased brain function that is demonstrated as sleepiness, inability ... the POLG gene often result in a reduced number of copies of mtDNA (mtDNA depletion), particularly in ...