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  1. Nearsightedness 
    ... such as when driving) than things that are close up (such as when reading or using a ... commonly autosomal dominant, autosomal recessive, or X-linked. Close sighted Myopia Myopic Near-sightedness Nearsighted Short-sighted ...
    https://medlineplus.gov/genetics/condition/nearsightedness - Genetics
  2. Spina bifida 
    ... into the brain and spinal cord, fails to close completely during the first few weeks of embryonic ... the bones of the spinal column do not close completely around the developing nerves of the spinal ...
    https://medlineplus.gov/genetics/condition/spina-bifida - Genetics
  3. Coloboma 
    ... known as the choroidal fissure or embryonic fissure) closes to form the structures of the eye. When the optic fissure does not close completely, the result is a coloboma.Because the ...
    https://medlineplus.gov/genetics/condition/coloboma - Genetics
  4. X-linked cardiac valvular dysplasia 
    ... heart valves is thickened and cannot open and close completely when the heart beats and pumps blood. ... impairs the valve's ability to open and close when the heart pumps blood. In addition, it ...
    https://medlineplus.gov/.../x-linked-cardiac-valvular-dysplasia - Genetics
  5. 22q11.2 deletion syndrome 
    ... the roof of the mouth (palate) may not close completely, even though the tissue covering them does, ... from the loss of many genes that are close together.Researchers are working to identify all of ...
    https://medlineplus.gov/genetics/condition/22q112-deletion-syndrome - Genetics
  6. Farsightedness 
    ... farsighted have more trouble seeing things that are close up (such as when reading or using a ... general, older adults also have difficulty seeing things close up; this condition is known as presbyopia. Presbyopia ...
    https://medlineplus.gov/genetics/condition/farsightedness - Genetics
  7. Vitiligo 
    ... the hands, arms, and places where bones are close to the skin surface (bony prominences). Another form ... people with this condition have at least one close relative who is also affected. Vitiligo National Organization ...
    https://medlineplus.gov/genetics/condition/vitiligo - Genetics
  8. Permanent neonatal diabetes mellitus 
    ... cells of the pancreas. These channels open and close in response to the amount of glucose in ... result in K-ATP channels that do not close, leading to reduced insulin secretion from beta cells ...
    https://medlineplus.gov/.../permanent-neonatal-diabetes-mellitus - Genetics
  9. Anencephaly 
    ... a structure called the neural tube fails to close during the first few weeks of embryonic development. ... tube defect.Because the neural tube fails to close properly, the developing brain and spinal cord are ...
    https://medlineplus.gov/genetics/condition/anencephaly - Genetics
  10. Cleidocranial dysplasia 
    ... are narrow and sloping, can be brought unusually close together in front of the body, and in ... on the heads of infants. The fontanelles normally close in early childhood, but they may remain open ...
    https://medlineplus.gov/genetics/condition/cleidocranial-dysplasia - Genetics
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