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Absence of peroxisomes
- ... severe Zellweger spectrum disorder are due to the absence of functional peroxisomes within cells. Intermediate and mild Zellweger spectrum disorder ...
- ... alpha-oxidation, which occurs in cell structures called peroxisomes. These sac-like compartments contain enzymes that process ... or PEX7 gene disrupt the usual functions of peroxisomes, including the breakdown of phytanic acid. As a ...