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URIC ACID
- ... functional mechanisms underlying SLC2A9 associations with human serum uric acid. Hum Mol Genet. 2014 Oct 1;23(19): ...
- The SLC22A12 gene provides instructions for making a protein called urate transporter 1 (URAT1). This protein is found in the kidneys, specifically in structures ...
- The ABCG2 gene belongs to a group of genes called the ATP-binding cassette family; genes in this family provide instructions for making proteins that transport ...
- ... amounts of purines are generated.Under these conditions, uric acid, a waste product of purine breakdown, accumulates in the body. A buildup of uric acid can cause gout, which is a form of ...
- ... called xanthine, and the conversion of xanthine to uric acid, a waste product that is normally excreted in ... purine breakdown. Because xanthine is not converted to uric acid, affected individuals have high levels of xanthine and ...
- ... low-function hypoxanthine phosphoribosyltransferase 1. Under these conditions, uric acid, a waste product of purine breakdown, accumulates in ... and can cause gouty arthritis (arthritis caused by uric acid in the joints), kidney stones, and bladder stones. ...
- ... called xanthine, and the conversion of xanthine to uric acid, a waste product that is normally excreted in ... dehydrogenase activity prevents the conversion of xanthine to uric acid, leading to an accumulation of xanthine in the ...
- ... hypoxanthine, and low levels of another chemical called uric acid. (Testing for these chemicals can help in the ...
- ... hypoxanthine, and low levels of another chemical called uric acid. (Testing for these chemicals can help in the ...
- ... recognizes bacteria; chemicals such as asbestos, silica, and uric acid crystals; and compounds released by injured cells.Cryopyrin ...