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Results 1 - 2 of 2 for IBRUTINIB
  1. PLCG2 gene 
    ... Several PLCG2 gene mutations have been associated with ibrutinib resistance, which is a condition in which the drug ibrutinib becomes ineffective in people with these mutations. Ibrutinib ...
    https://medlineplus.gov/genetics/gene/plcg2 - Genetics
  2. CXCR4 gene 
    ... activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of ... CXCR4 WHIM-like frameshift and nonsense mutations promote ibrutinib resistance but do not supplant MYD88(L265P) -directed ...
    https://medlineplus.gov/genetics/gene/cxcr4 - Genetics