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Cerebral inclusion bodies
- ... to one another and form clumps called neuroserpin inclusion bodies or Collins bodies. These clumps disrupt the cells' normal functioning and ultimately lead to cell death. The gradual loss of neurons in certain parts of the brain causes progressive dementia in people with FENIB.SERPINI1 ...
- ... gene have been identified in people who have inclusion body myopathy with ... a brain condition called frontotemporal dementia that worsens over time. ...
- ... birth. Huntingtin is found in many of the body's tissues, with the highest levels of activity in the brain. Within cells, this protein may be involved in ...
- ... embryonic development to control the formation of many body structures. Specifically, the ARX protein is believed to be involved in the development of the brain, pancreas, testes, and muscles used for movement (skeletal ...
- ... atrophy) and cannot transmit visual information to the brain. As the optic nerves atrophy, vision worsens, leading to the signs and symptoms of optic atrophy type 1.While the OPA1 protein is found in cells throughout the body, retinal ganglion cells appear to be particularly sensitive ...
