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Central precocious puberty 1
- ... of a novel MKRN3 missense mutation in familial central precocious puberty. Clin Endocrinol (Oxf). 2016 Jan;84(1):80-4. doi: 10.1111/cen.12854. Epub ... maternally imprinted gene MKRN3 are common in familial central precocious puberty. Eur J Endocrinol. 2016 Jan;174(1):1-8. doi: 10.1530/EJE-15-0488. ...
- ... in boys and men with familial male-limited precocious puberty. These mutations replace single protein building blocks (amino ... excess of testosterone, leading to familial male-limited precocious puberty. Affected boys begin exhibiting the signs of puberty, ...