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Abnormality of cranial sutures
- ... imply an unexpected role for hedgehog signaling in cranial-suture development and obesity. Am J Hum Genet. 2007 ...
- ... causes premature joining of the bones of the skull (craniosynostosis), leading to a misshapen head and distinctive facial features. It also causes a skin abnormality called acanthosis nigricans that is characterized by thick, ...