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Abnormal demyelination
- ... of this enzyme's function may result in abnormal myelin that is prone to deterioration (demyelination), leading to a loss of white matter (leukodystrophy). ...
- ... In people with ADLD, the loss of myelin (demyelination) occurs in the brain and spinal cord (central nervous system), often years before movement problems develop. Demyelination of the spinal cord likely contributes to the ...
- ... activities, leading to instability and loss of myelin (demyelination). Demyelination reduces the ability of the peripheral nerves to ... normal functions of the Schwann cell, leading to demyelination and producing the signs and symptoms of CMT1A. ...