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Abnormal coagulation factor V activity
- ... affected individuals have a greatly increased risk of abnormal bleeding episodes, including life-threatening bleeding inside the skull (intracranial hemorrhage). F13A1 gene mutations severely reduce the amount or activity of the A subunit of factor XIII. In ...
- ... blood clotting, which causes the increased risk for abnormal blood clots in protein C deficiency.Mutations that cause protein C deficiency type II result in the production of an altered protein C with reduced activity. Individuals with this form of the condition have ...
- ... affected individuals have a greatly increased risk of abnormal bleeding ... of factor XIII activity weakens new blood clots and prevents them from ...