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Abnormal T cell activation
- ... these lymphomas; neoplasia is a general term meaning abnormal growths of tissue.MAGT1 gene mutations impair the magnesium transporter's function, reducing the amount of magnesium that gets into T cells. This magnesium deficiency prevents the efficient activation of the T cells to target EBV and ...
- ... of being broken down, which may contribute to abnormal activation of immune cells or cell damage and death. ... Central Schulman BA, Harper JW. Ubiquitin-like protein ... Z, Gu X, Li F, Lou T, Ji C, Mao Y. Expression, purification and characterization ...
- ... with accelerated disease progression in certain cancers.The abnormal activation and increased activity of the FGFR4 gene are ...
- ... the time (constitutively active), which leads to the abnormal activation of certain genes. These genes increase the proliferation ...
- ... These abnormal cells, however, cannot respond to infections. T cells are also abnormal and unable to fight foreign invaders (a phenomenon ... 11; CARD11 B-CELL EXPANSION WITH NFKB AND T-CELL ANERGY; BENTA IMMUNODEFICIENCY 11A; IMD11A ... caused by a dominant negative mutation in caspase activation and recruitment domain family member 11 (CARD11). J ...
- ... Tian L, Joensuu T, Kopra O, Lehesjoki AE. Abnormal microglial activation in the Cstb(-/-) mouse, a model for progressive ...
- ... HUMAN gp39 hCD40L HIGM1 IGM IMD3 T-B cell-activating molecule T-BAM TNF-related activation protein TNFSF5 TRAP tumor necrosis factor (ligand) superfamily ...
- ... disorder. Studies suggest that these genetic changes enhance activation of NF-κB, resulting in abnormal inflammation, which is a characteristic feature of psoriasis. ...
- ... are described as "loss-of-function" because the abnormal or missing C3 protein prevents normal activation of the complement system. As a result, the ...
- ... such as those found within the skin. The abnormal cells die too easily, resulting in reduced numbers of these cells. A shortage of T cells impairs the immune response to foreign invaders, ...