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Results 1 - 9 of 9 for TP53
  1. Li-Fraumeni syndrome 
    ... Fraumeni syndrome is associated with mutations in the TP53 gene. Nearly three-quarters of families with Li- ... Fraumeni-like syndrome have germline mutations in the TP53 gene. Germline mutations are typically inherited and are ...
    https://medlineplus.gov/genetics/condition/li-fraumeni-syndrome - Genetics
  2. Lung cancer 
    ... s cells (germline mutations).Somatic mutations in the TP53, EGFR, and KRAS genes are common in lung cancers. The TP53 gene provides instructions for making a protein, called ...
    https://medlineplus.gov/genetics/condition/lung-cancer - Genetics
  3. Bladder cancer 
    ... Somatic mutations in the FGFR3, PIK3CA, KDM6A, and TP53 genes are common in bladder cancers. Each of ... FGFR3 HRAS KDM6A KMT2D PIK3CA PTEN RAF1 RB1 TP53 chromosome 9 Additional Information from NCBI Gene: CCNE1 ...
    https://medlineplus.gov/genetics/condition/bladder-cancer - Genetics
  4. Breast cancer 
    ... which is usually caused by mutations in the TP53 gene; and Peutz-Jeghers syndrome, which typically results ... FGFR2 H19 MAP3K1 NBN PTEN RAD51 STK11 TERT TP53 Additional Information from NCBI Gene: BARD1 BRIP1 CASP8 ...
    https://medlineplus.gov/genetics/condition/breast-cancer - Genetics
  5. Head and neck squamous cell carcinoma 
    ... several of the genes associated with HNSCC, including TP53, NOTCH1, and CDKN2A, function as tumor suppressors, which ... progression of HNSCC. CDKN2A HRAS NOTCH1 PIK3CA PTEN TP53 Additional Information from NCBI Gene: FAT1 HNSCC is ...
    https://medlineplus.gov/.../head-and-neck-squamous-cell-carcinoma - Genetics
  6. Ovarian cancer 
    ... mutations, are not inherited. Somatic mutations in the TP53 gene occur in almost half of all ovarian ... MLH1 MSH2 MSH6 NBN PIK3CA PMS2 PRKN STK11 TP53 Additional Information from NCBI Gene: BARD1 BRIP1 CHEK2 ...
    https://medlineplus.gov/genetics/condition/ovarian-cancer - Genetics
  7. Wilms tumor 
    ... development of Wilms tumor. AMER1 CTNNB1 H19 IGF2 TP53 WT1 Additional Information from NCBI Gene: DGCR8 DROSHA ...
    https://medlineplus.gov/genetics/condition/wilms-tumor - Genetics
  8. Cholangiocarcinoma 
    ... LAMA2 NF1 NRAS PIK3CA PTEN RB1 SMAD4 TERT TP53 TSC1 Additional Information from NCBI Gene: ARAF CDK6 ...
    https://medlineplus.gov/genetics/condition/cholangiocarcinoma - Genetics
  9. Melanoma 
    ... CDKN2A MC1R MITF NRAS OCA2 PLA2G6 SLC45A2 TERT TP53 TYR TYRP1 Additional Information from NCBI Gene: ASIP ...
    https://medlineplus.gov/genetics/condition/melanoma - Genetics