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Results 1 - 10 of 28 for Lower limb muscle weakness
  1. Spinal muscular atrophy with lower extremity predominance 
    Spinal muscular atrophy with lower extremity predominance (SMA-LED) is characterized by muscle weakness and wasting (atrophy) in the lower limbs, most severely affecting the thigh muscles (quadriceps). (In SMA-LED, the "D" stands ...
    https://medlineplus.gov/...atrophy-with-lower-extremity-predominance - Genetics
  2. Spinal muscular atrophy with progressive myoclonic epilepsy 
    ... years of normal development, affected children begin experiencing muscle weakness and atrophy in the lower limbs, causing difficulty walking and frequent falls. The muscles ...
    https://medlineplus.gov/...rophy-with-progressive-myoclonic-epilepsy - Genetics
  3. Fragile X-associated tremor/ataxia syndrome 
    ... have reduced sensation, numbness or tingling, pain, or muscle weakness in the lower limbs (peripheral neuropathy). Some people with FXTAS experience problems ...
    https://medlineplus.gov/...agile-x-associated-tremor-ataxia-syndrome - Genetics
  4. Spastic paraplegia type 3A 
    ... hereditary spastic paraplegias. These disorders are characterized by muscle stiffness (spasticity) and weakness in the lower limbs (paraplegia). Hereditary spastic paraplegias are often divided into ...
    https://medlineplus.gov/.../condition/spastic-paraplegia-type-3a - Genetics
  5. Spastic paraplegia type 5A 
    ... hereditary spastic paraplegias. These disorders are characterized by muscle stiffness (spasticity) and severe weakness in the lower limbs (paraplegia). Hereditary spastic paraplegias are often divided into ...
    https://medlineplus.gov/.../condition/spastic-paraplegia-type-5a - Genetics
  6. Lattice corneal dystrophy type II 
    ... cause loss of sensation and weakness in the limbs (peripheral neuropathy). Peripheral neuropathy usually occurs in the lower legs and arms, leading to muscle weakness, clumsiness, and difficulty sensing vibrations.The skin is ...
    https://medlineplus.gov/.../lattice-corneal-dystrophy-type-ii - Genetics
  7. Tubular aggregate myopathy 
    ... movement. This disorder causes muscle pain, cramping, or weakness that begins in childhood and worsens over time. The muscles of the lower limbs are most often affected, although the upper limbs ...
    https://medlineplus.gov/.../condition/tubular-aggregate-myopathy - Genetics
  8. Action myoclonus–renal failure syndrome 
    ... jerks typically occur in the torso; upper and lower limbs; and face, particularly ... and weakness in the limbs (peripheral neuropathy), or hearing loss ...
    https://medlineplus.gov/.../action-myoclonus-renal-failure-syndrome - Genetics
  9. Infantile-onset ascending hereditary spastic paralysis 
    ... and complicated. The pure types involve only the lower limbs, while the ... progresses, the muscles in the arms, neck, and head become involved ...
    https://medlineplus.gov/...et-ascending-hereditary-spastic-paralysis - Genetics
  10. Silver syndrome 
    ... types: pure and complex. Both types involve the lower limbs; the complex ... syndrome is usually weakness in the muscles of the hands. These muscles ...
    https://medlineplus.gov/genetics/condition/silver-syndrome - Genetics
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