- NLM Digital Collections - Modulator treatments for cystic fibrosis : effectiveness and valuePublication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, April 27, 2020... 4.4 (0 to without appropriate 18.3) washout Placebo: 7.3 (5.2 to 8.2) Difference ... between) 98.5 (6.4) difference (p-value) washout for 4 −2.22 (p=0.0097) weeks, and 150mg placebo every 12 hours for 4 weeks OR (2) ...
- NLM Digital Collections - Modulator treatments for cystic fibrosis : effectiveness and value : final evidence report ...Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, June 7, 2018... four- weeks, and 150mg Mean, percentage value) week washout placebo every 12 hours points (SD) −2.22 (p= ... twice daily, BMI Ivacaftor: 83.33 28-day washout period, Mean, kg (SD) Placebo: 79.97 (1) 22.7 (6.96) ©Institute ...
- NLM Digital Collections - Single-Drug Therapy for Hypertension in Men: A Comparison of Six Antihypertensive Agents with ...Publication: Massachusetts Medical Society, 1 April 1993... of 95 to 109 mm Hg, after a placebo washout period, to receive placebo or one of six ... maintenance phase, each patient entered a four-week placebo washout phase. Patients who had been randomly assigned to ...
- NLM Digital Collections - Response to a Second Single Antihypertensive Agent Used as Monotherapy for Hypertension after ...Publication: The American Medical Association, 11 September 1995... failed an active treatment and withdrew during the placebo washout phase, the com- bined response rate was 76. ...
- NLM Digital Collections - Vesicular monoamine transporter 2 inhibitors for tardive dyskinesia : effectiveness and value ...Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, December 22, 2017... 17.8) followed by 4 (combined w/ prior placebo disorder/mood disorder, n (%) weeks washout group) 2) 61 (64.9)/33 (35.1) ... 7 (9.6) 2) 2.4 VE and Washout periods 2) 47.2 (11.2) 3) 2.2 2) VBZ 40 mg/day, n=97 3) 47.6 (13.6) (combined w/ prior placebo group) Male, n (%) 1) 34 (68.0) 3) ...
- NLM Digital Collections - Targeted immunomodulators for the treatment of moderate-to-severe plaque psoriasis : ...Publication: Boston, MA : Institute for Clinical and Economic Review, December 2 2016... doses of brodalumab URIs (≥5% in any or placebo DLQI: HADS-A (treatment group): Exclusion: A washout difference, after 1) 8.2, 2) 8.1, 3) 6.4 period was required NR imputation): for patients receiving PsA (%): 1) -1.3, 2) -1.5 ... supplementary p<0.001 appendix) Previous biologics (%): HADS- ...
- NLM Digital Collections - Primary care services : promoting optimal child development from birth to three yearsPublication: New York, NY : Commonwealth Fund, [2002]... 2 week baseline–4 weeks of drug or placebo–1 week washout–4 weeks of Limitations to generalizability: This sample ...
- NLM Digital Collections - Mavacamten for hypertrophic cardiomyopathy : effectiveness and value : final evidence report ....Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, November 16, 2021... but partially recovered to LVEF 50% during the washout period. Three patients on mavacamten and three patients on placebo temporarily discontinued due to changes in QT interval. ...
- NLM Digital Collections - Abuse-deterrent formulations of opioids : effectiveness and value : final evidence reportPublication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, August 8, 2017... oxycodone 4) 73.7 (14.9) 20mg or placebo in a double- 5) 75.4 (16.8) blind, crossover with 24-hr 6) 52.7 (13.4) washout between. *p<0.0001 vs. IR oxycodone Intact ...
- NLM Digital Collections - Oxprenolol vs Propranolol: A Randomized, Double-Blind, Multiclinic Trial in Hypertensive ...Publication: American Heart Association, [March-April 1981]... determined during the prerandomization period. Following a drug washout period of 4 weeks, if patients were on prior therapy they were given a bottle containing placebo, identical in appearance to the drugs used in ...
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