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52 results
  1. NLM Digital Collections - Modulator treatments for cystic fibrosis : effectiveness and value 
    Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, April 27, 2020
    ... 4.4 (0 to without appropriate 18.3) washout Placebo: 7.3 (5.2 to 8.2) Difference ... between) 98.5 (6.4) difference (p-value) washout for 4 −2.22 (p=0.0097) weeks, and 150mg placebo every 12 hours for 4 weeks OR (2) ...
  2. ... of 95 to 109 mm Hg, after a placebo washout period, to receive placebo or one of six ... maintenance phase, each patient entered a four-week placebo washout phase. Patients who had been randomly assigned to ...
  3. NLM Digital Collections - Modulator treatments for cystic fibrosis : effectiveness and value : final evidence report ... 
    Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, June 7, 2018
    ... four- weeks, and 150mg Mean, percentage value) week washout placebo every 12 hours points (SD) −2.22 (p= ... 4) for 4 weeks OR (2) 150mg of placebo every 12 hours for 4 weeks, washout for 4 weeks, and 150mg ivacaftor every 12 ...
  4. ... failed an active treatment and withdrew during the placebo washout phase, the com- bined response rate was 76. ...
  5. NLM Digital Collections - Vesicular monoamine transporter 2 inhibitors for tardive dyskinesia : effectiveness and value ... 
    Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, December 22, 2017
    ... 17.8) followed by 4 (combined w/ prior placebo disorder/mood disorder, n (%) weeks washout group) 2) 61 (64.9)/33 (35.1) ... 7 (9.6) 2) 2.4 VE and Washout periods 2) 47.2 (11.2) 3) 2.2 2) VBZ 40 mg/day, n=97 3) 47.6 (13.6) (combined w/ prior placebo group) Male, n (%) 1) 34 (68.0) 3) ...
  6. NLM Digital Collections - Targeted immunomodulators for the treatment of moderate-to-severe plaque psoriasis : ... 
    Publication: Boston, MA : Institute for Clinical and Economic Review, December 2 2016
    ... doses of brodalumab URIs (≥5% in any or placebo DLQI: HADS-A (treatment group): Exclusion: A washout difference, after 1) 8.2, 2) 8.1, 3) 6.4 period was required NR imputation): for patients receiving PsA (%): 1) -1.3, 2) -1.5 ... supplementary p<0.001 appendix) Previous biologics (%): HADS- ...
  7. ... 2 week baseline–4 weeks of drug or placebo–1 week washout–4 weeks of Limitations to generalizability: This sample ...
  8. NLM Digital Collections - Mavacamten for hypertrophic cardiomyopathy : effectiveness and value : final evidence report .... 
    Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, November 16, 2021
    ... but partially recovered to LVEF 50% during the washout period. Three patients on mavacamten and three patients on placebo temporarily discontinued due to changes in QT interval. ...
  9. NLM Digital Collections - Abuse-deterrent formulations of opioids : effectiveness and value : final evidence report 
    Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, August 8, 2017
    ... oxycodone 4) 73.7 (14.9) 20mg or placebo in a double- 5) 75.4 (16.8) blind, crossover with 24-hr 6) 52.7 (13.4) washout between. *p<0.0001 vs. IR oxycodone Intact ...
  10. ... determined during the prerandomization period. Following a drug washout period of 4 weeks, if patients were on prior therapy they were given a bottle containing placebo, identical in appearance to the drugs used in ...
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