... labeled DNA probes demonstrated that levels of c-myc mRNA are transiently eleva few hours after the initiation of differentiation in vitro, c-myc mRNA seems to be post-transcriptionally regulated, as ...

... i^ /' . 7 A Ft}/. IF V ■;■ :^i ss-'-p*-^ ;: " - myC . fr.l./fi-n; W$!i :<f^s;M ™' ...

... Cells: Coordinate Regulation with c-fos or c-myc ... Cells: Coordinate Regulation with c-fos or c-myc RNA, Messenger 3T3 Cells National Academy of Sciences ( ...

... nuclear proto-oncogene messenger ribonucleic acid (mRNAs) (c-myc, N-myc, c-fos, c-jun, Rb, and p53) and ... deregulation of c-fos, c-jun, and c-myc expression during apoptosis. We have demonstrated that expression ...

... modulation is not associated with downregulation of N-myc oncogene expression. These observations indicate that IFN-y- ... effects were not associated with downregulation of N-myc oncogene nuclear transcription. Moreover, dexamethasone did not affect ...

... modulation is not associated with downregulation of N-myc oncogene expression. These observations indicate that IFN-y- ... were not associated with down-regulation of N-myc oncogene nuclear transcription. Moreover, dexamethasone did not affect ...

... discovery of distinct viral oncogenes, such as Src, Myc, and Ras, and their cellular precursors, called proto- ... perspective R Nusse and H Varmus the c-myc gene and that c-myc was overexpressed in ...

... early experiment pointing to oncogene addiction involved the MYC oncogene. In 1999, Dean Felsher and Michael Bishop ... of California San Francisco inserted into mice a MYC gene that they (the researchers) could control at ...

... interesting way from Hayward's: (next slide: diagram of myc) all of his tumors contained proviruses positioned so ... an LTR could provide a promoter for c-myc. However, several of our tumors had proviruses arranged ...

... the genes (especially src, Wnt-l/int-1, myc, and their relatives) implicated in retrovirus-induced neoplasia. ( ... transformation. * Generation of a large collection of c-myc mutants that allowed definition of functional domains of ...