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21 results
  1. NLM Digital Collections - Assessment, diagnosis and clinical interventions for children and young people with autism ... 
    Publication: Edinburgh, Scotland : SIGN, [2007]
    resource.nlm.nih.gov/101321862
    ... Ensure patient and family are fully informed that melatonin is not a licensed medication, which limits the information that is available about effectiveness and safety. 6.8 OTHER TREATMENTS There is insufficient good ...
  2. NLM Digital Collections - Assessment, diagnosis and interventions for autism spectrum disorders : a national clinical ... 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), June 2016
    resource.nlm.nih.gov/101714471
    ... symptoms. yy Long-term study of the efficacy, safety and cost effectiveness of melatonin compared to behavioural interventions for managing sleep problems. ...
  3. NLM Digital Collections - Epilepsies in children and young people : investigative procedures and management : a ... 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), May 2021
    resource.nlm.nih.gov/9918334378406676
    ... parent or carer driving to the appointment." The safety of sleep deprivation ... consideration. Melatonin-induced sleep An alternative way to obtain a ...
  4. NLM Digital Collections - Calcitonin gene-related peptide (CGRP) inhibitors as preventive treatments for patients with .... 
    Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, July 3, 2018
    resource.nlm.nih.gov/101744957
    ... Ossipov MH, Kim BK, Yang JY. Efficacy and safety of galcanezumab for the ... trial comparing melatonin 3 mg, amitriptyline 25 mg and placebo for ...
  5. NLM Digital Collections - Risk reduction and management of delirium : a national clinical guideline 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), March 2019
    resource.nlm.nih.gov/101772268
    ... reviews identified four RCTs on the use of melatonin to prevent delirium in medical and 1++ surgical ... One small RCT in 88 patients found a melatonin 1+ receptor agonist reduced the incidence (24.4% ...
  6. NLM Digital Collections - Management of patients with dementia : a national clinical guideline 
    Publication: Edinburgh, Scotland : SIGN, [2006]
    resource.nlm.nih.gov/101271578
    ... wake cycle. Bright light affects the production of melatonin, which may lessen these problems. Bright light therapy ... people with Alzheimer’s disease. 4.8.2melatonin Exogenous melatonin is not effective in reducing sleep disturbance associated ...
  7. NLM Digital Collections - 4/27/1982-6/24/1983 
    https://resource.nlm.nih.gov/101637321X3
    ... Sis-cWer ical! with the secretion of the melatonin, and serstonin resrect- ively. |. - Lo _ | | May I state, ... in all ofthe aforementioned conditions. The pineal secretes melatonin to serve to prevent and cure of most ...
  8. NLM Digital Collections - Annual report - National Eye Institute (1981) 
    Publication: [Bethesda, Md.] : National Eye Institute
    resource.nlm.nih.gov/7802080X10
    ... cases, 24-hour urine, levels of hormones including melatonin , Cortisol, thyroid and zinc are being determined. By ... of various retinal degenerative conditions will be elucidated. Melatonin rhythnts are being studied in individuals blinded from ...
  9. NLM Digital Collections - Review of intramural research (1960) 
    Publication: [Bethesda, Md.] : U.S. Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health
    resource.nlm.nih.gov/0141176X2
    ... of serotonin leads to the pineal gland hormone, melatonin (N-acetyl-5-methoxytryptamine). In conjunction with members ... is first acetylated and then methylated to yield melatonin. The two enzymes have been partially purified and ...
  10. NLM Digital Collections - Annual report - National Eye Institute (1977) 
    Publication: [Bethesda, Md.] : National Eye Institute
    resource.nlm.nih.gov/7802080X6
    ... in a solution containing radioactive sugars and/ or melatonin . Both autoradiography and phagosome counts are made to ... segments for shedding, and to see if the melatonin plays a role in controlling this process. 91 ...
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