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452 results
  1. NLM Digital Collections - E19 : a selective approach to safety data collection in specific late-stage preapproval or ... 
    Publication: Silver Spring, MD : Center for Drug Evaluation and Research, December 2022
    ... surrogate endpoint, e.g., blood pressure, haemoglobin A1c, creatinine clearance. If the safety profile has been well characterized, selective safety data ...
  2. NLM Digital Collections - Management of chronic heart failure : a national clinical guideline 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), March 2016
    ... 5 mmol/l is acceptable. yy If urea, creatinine or potassium do rise ... dose of diuretic. The safety and efficacy of an ACE inhibitor used with ...
  3. ... 129 Cream of tartar, 103,167 Creatine, 186 Creatinine, 186 Crystallization, ... needle, 26 j Davy's safety lamp, 148 1 Determination of chlorides, 105 I ...
  4. ... to be effective. Before the Kefauver amendment only safety bad to be shown for new drugs. Well• we couldn't initially do anything about Krebiozen when Krebioaen was::mothing but mineral oil. We ...
  5. ... between treatment groups by the log-rank test. Safety Analyses The distributions of minimal white-cell counts, hemoglobin lev- els, platelet counts, and maximal serum creatinine concentrations were compared between treatment groups by Pearson’s ...
  6. ... Route of administration: Oral Purpose: To determine the safety and ... a week. inclusion criteria: Creatinine under 3.0 Age: 13 and over Sex: ...
  7. ... when it obviously was disabling. The preoperative serum creatinine level ... safety of elective vascular surgery.®!? Accordingly, we routinely perform ...
  8. NLM Digital Collections - Cancer clinical trial eligibility criteria : patients with organ dysfunction or prior or ... 
    Publication: [Silver Spring, MD] : United States Food and Drug Administration, Oncology Center of Excellence, July 2020
    ... glomerular filtration rate rather than an absolute serum creatinine ... development, safety profile of the product, understanding of the effect ...
  9. ... diagnosis of kidney failure was based on serum creatinine levels greater than 120 micromoles/L on two ... improve renal function in patients whose preoperative serum creatinine levels are less than 350 umoles/L. In ...
  10. NLM Digital Collections - Chemistry of the carbon compounds, or, Organic chemistry 
    Publication: Philadelphia : P. Blakiston, Son & Co., 1886
    ... hydantoin, C3H3(CII3)N202, was first obtained from creatinine, and is also formed when sarcosine (p. 293) ... few of them, however, are known. Creatine and creatinine, compounds of great significance physiologically, belong in this ...
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