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186 results
  1. NLM Digital Collections - Annual report - National Eye Institute (1993) 
    Publication: [Bethesda, Md.] : National Eye Institute
    resource.nlm.nih.gov/7802080X20
    ... T, Itabe H, Kador PF, Miller DD: Selective irreversible inhibitors of aldose reductase. J Med Chem 35:1117- ...
  2. NLM Digital Collections - Annual report - National Eye Institute (1994) 
    Publication: [Bethesda, Md.] : National Eye Institute
    resource.nlm.nih.gov/7802080X21
    ... 2 ceUs. (3) MDL 28,842, a potent irreversible inhibitor of S-adenosyl-L-homocysteine hydro- lase was shown ...
  3. NLM Digital Collections - Review of intramural research (1961) 
    Publication: [Bethesda, Md.] : U.S. Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health
    resource.nlm.nih.gov/0141176X3
    ... chains would be more effective and per- haps irreversible inhibitors of the enzymes : -NH2 phenylethylamine (substrate) H E — ...
  4. NLM Digital Collections - Perioperative blood transfusion for elective surgery : a national clinical guideline 
    Publication: Edinburgh, Scotland : SIGN, 2001
    resource.nlm.nih.gov/101134791
    ... myocardial 1+ revascularisation.131,132 Aspirin is an irreversible inhibitor of cyclo-oxygenase, which platelets (unlike vascular endothelium) ...
  5. NLM Digital Collections - Symposium on Military Physiology : under the auspices of the Military Establishment Research .... 
    Publication: Washington, D.C. : Military Establishment Research and Development Board, Committee on Geographical Exploration, Panel on Physiology, [1947?]
    resource.nlm.nih.gov/06830900R
    ... new type of drugs to the pharmacological armamentarium - irreversible cholinesterase inhibitors lacking any independent pharmacological ac- tion. This is ...
  6. NLM Digital Collections - Vesicular monoamine transporter 2 inhibitors for tardive dyskinesia : effectiveness and value ... 
    Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, December 22, 2017
    resource.nlm.nih.gov/101723938
    ... potentially important advancement for individuals with this frequently irreversible condition. In particular, for individuals with severe disabling TD, the use of VMAT2 inhibitors may decrease caregiver/family burden. ©Institute for Clinical ...
  7. NLM Digital Collections - Advances in military medicine: advances in military medicine made by American investigators ... 
    Publication: Boston : Little, Brown and Company, 1948
    resource.nlm.nih.gov/32430610RX2
    ... oxidize the —SH groups of the enzyme in irreversible fashion. Since the action of the most powerful known water-disinfecting agents seems to be as specific enzyme inhibitors, it appears that one should look to other ...
  8. NLM Digital Collections - Targeted immune modulators for rheumatoid arthritis : effectiveness and value : evidence ... 
    Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, April 7, 2017
    resource.nlm.nih.gov/101723892
    ... effects, including reversible corneal deposits are uncommon and irreversible ... inhibitor that works by inhibiting dihydroorotate dehydrogenase and is ...
  9. NLM Digital Collections - Review of intramural research (1960) 
    Publication: [Bethesda, Md.] : U.S. Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health
    resource.nlm.nih.gov/0141176X2
    ... drug administration in long-term therapy 82 Biochemically irreversible drugs 82 ... inhibitors 83 Hypotensive drugs — guanethidine and bre- tylium 83 ...
  10. NLM Digital Collections - Annual report - National Eye Institute (1992) 
    Publication: [Bethesda, Md.] : National Eye Institute
    resource.nlm.nih.gov/7802080X19
    ... D: Novel alrestatin analogs with potent reversible and irreversible inhibitory activity for ... Endocrine Soc 10A:15, 1992. Kador PF: Intermediary ...
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