... of normal cultured cells 128 Viral synthesis 129 Galactosemia cell cultures i29 Laboratory of germ-free animal ... acid (DNA) and that of the mature virus. Galactosemia Cell Cultures An exciting new development has been ...

... two subjects who had typical symptoms of congenital galactosemia in infancy and who now have no detectable ... from a single galacto- semic patient indicates that galactosemia is a more complex disease entity than has ...

... glucose metabolism. Studies have suggested that heterozygotes for galactosemia show relatively low levels of galactokinase (GK) and/ ... high plasma sugar concentrations encountered in diabetes and galactosemia, aldose reductase converts these sugars to their respective ...

... which results in more intracellular polyol accumulation in galactosemia. We fed rats galactose for extended periods in an effort to produce diabetic-like retinal lesions. Galactosemia did indeed induce diabetic-like microangiopathies that were ...

... lens through the sorbitol pathway in diabetes and galactosemia. Activity of aldose reductase in diabetic lens was ... galactosemic lens. Findings suggest that in diabetes and galactosemia, conditions in the lens are so altered as ...

... been demonstrated. Similar diseases are acatalasia, phenylketonuria and galactosemia; probably in all these an enzyme is effectively ... to the point where it becomes toxic. In galactosemia, the enzyme galactose-1-phosphate- transferase is not ...

... and hormones . . . Insulin Humoral agents in uremia Pyrophosphatase Galactosemia Steroid hormones Nucleic acids Cell-free protein synthesis ... InsuUn 212 Glycogen storage disease 213 Galactose and galactosemia 213 Amino acid Transport and protein synthesis . 213 ...

... metabolism 264 Glucose Transport 264 Galactose Metabolism and Galactosemia 264 Amino Acid Transport 264 Protein Structure 265 ... now at NIAMD. The precise biochemical lesions in galactosemia, xanthinuria, homocystinuria, cystinuria, cystathioninuria, and gout have been ...

... high plasma sugar concentrations encountered in diabetes and galactosemia, aldose reductase converts these sugars to their respective ... ciliary process structure changes associated with diabetes and galactosemia. In addition, methods for either delaying or preventing ...

... Our present techniques for the accurate diagnosis of galactosemia depend on basic studies on the metabolism of ... mongolism; a homozygous recessive gene in phenylketonuria or galactosemia. By differentiating specific diseases within the complex of ...