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37 results
  1. ... a second and more limited proposal titled Donor Clonal Deletion for Transplantation which also involved lymphocyte traffic manipulation. ... N.I.H. grant (DK 37897) from DONOR CLONAL DELETION FOR TRANSPLANTATION to IMMUNOMODULATION BY HIV(AIDS) AND ...
  2. ... confer invasiveness. Data were also consistent with the clonal origin of pathogenic E. coli strains. The Kl hybrid plasmid, pSR23, was mapped by restriction endo- nuclease digestion analysis. Deletion analysis and Tn5 induced trans- poson mutagenesis showed ...
  3. ... retrovirus-induced tumors or at least stimulates growth; clonal expansion of ... is proposed to be a deletion mutation that extends from a site within the ...
  4. ... immunological thinking of the mid 1950s for which "clonal selection" is the ... deletion and rearrangement and insertion. Instructive ideas had seemed ...
  5. ... individual clones of simian virus 40 mutants containing deletions, duplications ... arrangements in clonal isolates of polyoma defec- tive DNA. Proc. Nat. ...
  6. NLM Digital Collections - Annual report - National Eye Institute (1993) 
    Publication: [Bethesda, Md.] : National Eye Institute
    ... the cDNA and proteins detected by the mono- clonal antibodies may provide the framework on which to ... highest activity of HO-1. Using specific poly- clonal antibodies and PCR-generated probes, we have demonstrated ...
  7. NLM Digital Collections - Long term follow-up after administration of human gene therapy products 
    Publication: Silver Spring, MD : Center for Biologics Evaluation and Research, January 2020
    ... the risk of developing leukemias and premalignant conditions (clonal cell expansion) due to integration of gammaretroviral vectors ... of the dominant clone(s) is, and whether the clonal outgrowth observed results in any (hematologic) malignancies). We ...
  8. NLM Digital Collections - Annual report - National Eye Institute (1992) 
    Publication: [Bethesda, Md.] : National Eye Institute
    ... locaUzation of RPE associated epitopes recognized by mono- clonal antibodies in human RPE and their induc- tion ... is being studied using immimohistochemistry, histology, and mono- clonal antibodies against various cytokines. Treatment of uveitis. — (1) ...
  9. NLM Digital Collections - Annual report - National Eye Institute (1994) 
    Publication: [Bethesda, Md.] : National Eye Institute
    ... that systemic treatment with anti-IL-12 mono- clonal antibodies exacerbates the development of EIU. These findings ... attempt to produce a specific polyclonal and mono- clonal antibody to the HSP 708 that was isolated ...
  10. NLM Digital Collections - Review of intramural research (1960) 
    Publication: [Bethesda, Md.] : U.S. Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health
    ... clone of mouse tumor cells. By means of clonal analysis additional hereditary alterations in mor- phology, level ... capacity, and chromosomal constitution have been determined among clonal derivatives. Last year an initial attempt to identify " ...
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