... drugs or their dosing. Finally, the number of clinical events for the individual PCSK9 inhibitors is too small ... was made because no trials were designed with clinical events as the primary outcome, the number of events ...

... safety data show a low incidence of adverse clinical events. However, study results also show that there are ... Contraindications, Warnings, and Precautions and description of the clinical events ☐ Additional warnings noting limitations of safety information (e. ...

... latter disease. Relapses are among the rarest of clinical events, and one attack, as a rule, bestows immunity ... followed by a terminal coma. This order of clinical events is not observed Avhen metastatic purulent meningitis exists, ...

... rationale is included within the subsequent subheadings (costs, clinical events, mortality, utilities). ©Institute for Clinical and Economic Review, ... chronic use of OCS likely results in adverse clinical events and their associated costs. We assumed that doses ...

... below. All regimens were associated with reductions in clinical event rates relative to metformin alone, including approximately one ... line model, differences between third-line combinations in clinical event rates were modest, with the exception of congestive ...

... medical facility) were also considered to be crisis events. Clinical Benefits of Crizanlizumab Compared to optimal usual care ... 12 years: weight- drug in GBT-sponsored voxelotor Events Clinical Trials based dose pediatric clinical study 3. Sickle ...

... a high degree of accuracy using an electronic clinical event monitor that employs a set of signals created ... the performance characteristics of signals used by a Clinical Event Monitor to detect adverse drug reactions in the ...

... go on to have a further adverse cardiac event. Clinical risk markers are more appropriate for the selection ... relative RR) compared with femoral access. Net adverse clinical events were also lower (1.9% absolute 1++ RR, ...

... generally present a lower risk of delayed adverse events. Clinical data from LTFU observations of subjects that have ... such as blood), methods of monitoring tests, and clinical events of interest that will be monitored over the ...

... is detailed in Table D5 of Appendix D. Clinical Events Response to Treatment Response to treatment was measured ... on the frequency of dose escalation as an event, clinical interest lies in whether dose escalation provides a ...