- ... 10 ] Fluorescent in situ hybridization of the BCR/ABL translocation can be performed on the bone marrow aspirate ... count, splenomegaly, thrombocytosis, and identification of the BCR/ABL translocation.[ 1 ] The optimal front-line treatment for patients ...
- ... Alteration c-myc Burkitt's lymphoma Translocations Plasmacytoma e~-abl Myeloid leukemia Translocation (Philadelphia chromosome) c-myc Myeloid leukemia Amplification Apudoma ...
- NLM Digital Collections - The Molecular Genetics of Cellular OncogenesPublication: Annual Reviews, Inc., 1984... A., et al. 1983. Localization of the c-abl oncogene adjacent to a translocation breakpoint in chronic myelocytic leukaemia. Nature 306:239- ... Evidence for a common ancestor to src and abl cellular genes. Cell ... 1984. A variant translocation places the im- munoglobulin genes 3' to the ...
- ... mutations or variants . Other names: BCR-ABL , BCR-ABL fusion, Philadelphia chromosome, B-cell acute lymphoblastic leukemia (B-ALL), chronic myelogenous leukemia (CML), t(9;22), BCR-ABL1 Transcript Detection by RT-PCR, Quantitative BCR-ABL1 Translocation Detection by RT-PCR What is it used ...
- ... Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med. 1996 ... Chromosome Translocations on the Clinical Course of Chronic Myeloid Leukemia. ...
- ... individuals with HDL2 [ Walker et al 2003 ]. Abetalipoproteinemia (ABL) and hypobetalipoproteinemia (HBL) share acanthocytosis with ChAc and ... steatorrhea, and absence of basal ganglia movement disorder. ABL and HBL are caused by pathogenic variants in ...
- ... for This Gene Abelson tyrosine-protein kinase 1 ABL bcr/abl bcr/c-abl oncogene protein c-ABL c-abl oncogene 1, receptor tyrosine kinase c-ABL1 JTK7 p150 proto-oncogene c-Abl proto-oncogene tyrosine-protein kinase ABL1 tyrosine-protein ...
- ... synonym >Abetalipoproteinaemia</synonym><synonym >Abetalipoproteinemia neuropathy</synonym><synonym >ABL</synonym><synonym >Acanthocytosis</synonym><synonym >Apolipoprotein B deficiency</ ...
- ... UI 90274691 AU •WeitbergAB AU • Corvese D TI Translocation of chromosomes 16 and 18 in oxygen radical- ... MH Karyotyping MH -Lung MH -Oxygen/'TOXICrrY MH • 'Translocation (Genetics) SO - Biochem Biophys Res Commun 1990 May ...
- ... zipper, FATC, p53 binding Binding sites for: c-abl, p53, Bloom's protein Other homologies: DNA-PK, ... Chk2, MDM2, 53BP1, SMC1, BRCA1, FANCD2, H2AX, c-abl, nibrin, Mre11, KAP1 [ Linding et al 2007 , Matsuoka ...
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