Results 1 - 2 of 2 for ibrutinib
  1. ... Several PLCG2 gene mutations have been associated with ibrutinib resistance, which is a condition in which the drug ibrutinib becomes ineffective in people with these mutations. Ibrutinib ...
  2. ... activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of ... CXCR4 WHIM-like frameshift and nonsense mutations promote ibrutinib resistance but do not supplant MYD88(L265P) -directed ...