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Results 1 - 5 of 5 for Complement activation
  1. Neuromyelitis optica 
    ... inflammation, and remove debris from cells and tissues. Complement activation leads to the inflammation of the optic nerve ... L, Illes Z. A systematic analysis of the complement pathways in patients with ... but no activation during remission. Mol Immunol. 2014 Feb;57(2): ...
    https://medlineplus.gov/genetics/condition/neuromyelitis-optica - Genetics
  2. Complement factor I deficiency 
    ... complement factor I. The lack (deficiency) of functional complement factor I protein allows uncontrolled activation of the complement system. The unregulated activity of ...
    https://medlineplus.gov/.../condition/complement-factor-i-deficiency - Genetics
  3. Atypical hemolytic-uremic syndrome 
    ... hemolytic-uremic syndrome protect healthy cells by preventing activation of the complement system when it is not needed.Mutations in ... with atypical hemolytic-uremic syndrome lead to uncontrolled activation of the complement system. The overactive system attacks cells that line ...
    https://medlineplus.gov/.../atypical-hemolytic-uremic-syndrome - Genetics
  4. C3 glomerulopathy 
    ... to C3 glomerulopathy "turn up," or increase the activation of, the complement system. The overactive system damages structures called glomeruli ... can lead to ESRD. Studies suggest that uncontrolled activation of the complement system also causes the other health problems that ...
    https://medlineplus.gov/genetics/condition/c3-glomerulopathy - Genetics
  5. Complement component 2 deficiency 
    ... 2 protein. A lack of this protein impairs activation of the complement pathway. As a result, the complement system's ...
    https://medlineplus.gov/.../complement-component-2-deficiency - Genetics