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Broken ankle
- ... first symptoms of the disease. Several years later, broken bones (fractures) begin to occur frequently, particularly in the bones of the ankles, feet, wrists, and hands. Bone pain and fractures ...
- ... and feet and up to the wrists and ankles. The SLURP1 gene mutations involved in this condition lead to production of an altered SLURP-1 protein that is unstable and quickly broken down, if any protein is produced at all. ...
- ... joint deformities called contractures, particularly in the knees, ankles, and ... and easily broken down. As a result, people with Kuskokwim syndrome ...
- ... toe or other joints in the foot or ankle. If urate levels remain high, flares can recur, ... can lead to increased urate. When purines are broken down, urate is made, which can cause hyperuricemia ...
- ... Kuskokwim syndrome, contractures most commonly affect the knees, ankles, and elbows, although other joints, particularly of the ... the FKBP10 protein, making it unstable and easily broken down. As a result, people with Kuskokwim syndrome ...