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Lack of spontaneous play
- ... 1A. Affected infants may have severe muscle weakness, lack of muscle tone (hypotonia), little spontaneous movement, and joint deformities (contractures). Weakness of the ...
- ... an abnormal curvature of the spine (scoliosis), and spontaneous bone fractures. Some affected individuals have a smooth tongue that lacks the bumps that house taste buds (fungiform papillae). ...
- ... Progressive intracranial arterial occlusion Progressive intracranial occlusive arteropathy Spontaneous occlusion of the Circle of Willis Genetic Testing ...
- ... can be inherited or can occur spontaneously. Some spontaneous mutations associated with this condition occur during the ... found in every cell of the body. Other spontaneous mutations found in this condition, called somatic mutations, ...