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Results 1 - 10 of 33 for Abnormal drug response
  1. Malignant hyperthermia 
    ... open more easily and close more slowly in response to certain drugs. As a result, abnormally large amounts of calcium ions are released from storage within muscle cells. The abnormal increase in calcium ion concentration within muscle cells ...
    https://medlineplus.gov/genetics/condition/malignant-hyperthermia - Genetics
  2. Familial pityriasis rubra pilaris 
    ... overactivation of NF-κB signaling, which triggers an abnormal inflammatory response. Researchers are working to determine how these changes ... rubra pilaris: report of a family and therapeutic response to etanercept. J Drugs Dermatol. 2010 Jul;9(7):844-50. Citation ...
    https://medlineplus.gov/.../familial-pityriasis-rubra-pilaris - Genetics
  3. STAC3 disorder 
    ... malignant hyperthermia activate the RYR1 channel improperly in response to certain drugs. As a result, large amounts of calcium ions ...
    https://medlineplus.gov/genetics/condition/stac3-disorder - Genetics
  4. Crohn's disease 
    ... affects the digestive system. This condition involves an abnormal immune response that causes excess inflammation. It most often affects ...
    https://medlineplus.gov/genetics/condition/crohns-disease - Genetics
  5. Myasthenia gravis 
    ... for movement. In myasthenia gravis, because of the abnormal immune response, less AChR is present, which reduces signaling between ...
    https://medlineplus.gov/genetics/condition/myasthenia-gravis - Genetics
  6. Dystonia 16 
    ... proteins. The pattern of signals stimulated by these abnormal proteins in response to stress is altered, which increases the rate ...
    https://medlineplus.gov/genetics/condition/dystonia-16 - Genetics
  7. POR gene 
    ... the POR gene may influence a person's response to particular drugs (drug metabolism). More than 50 mutations in the ... resulting excess of that molecule can stimulate the abnormal growth and fusion ... of this enzyme in drug metabolism is an active area of research. More ...
    https://medlineplus.gov/genetics/gene/por - Genetics
  8. NLRP3 gene 
    ... the cryopyrin protein being overactive. Inflammasomes made with abnormal cryopyrin proteins trigger inflammatory responses even when there is no injury or disease. ...
    https://medlineplus.gov/genetics/gene/nlrp3 - Genetics
  9. Warfarin sensitivity 
    ... effect or take even longer to clear the drug from their body. Coumadin sensitivity Warfarin response Genetic Testing Registry: Warfarin response Warfarin sensitivity National ...
    https://medlineplus.gov/genetics/condition/warfarin-sensitivity - Genetics
  10. Clopidogrel resistance 
    ... clopidogrel Resistance to clopidogrel Genetic Testing Registry: Clopidogrel response National Organization for Rare Disorders (NORD) ClinicalTrials.gov DRUG METABOLISM, POOR, CYP2C19-RELATED PubMed Hirota T, Eguchi ...
    https://medlineplus.gov/genetics/condition/clopidogrel-resistance - Genetics
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