... the body. Most of the mutations that cause osteogenesisimperfectatype I occur in the COL1A1 gene. These genetic ... easily. The mutations responsible for most cases of osteogenesisimperfectatypes II, III, and IV occur in either the ...
ghr.nlm.nih.gov/condition/osteogenesis-imperfecta - External Health Links
... appearance and symptoms except for white sclerae. OI Type VIII is characterized by severe growth deficiency and extreme under-mineralization of the skeleton. It is caused by absence or severe deficiency of prolyl 3-hydroxylase activity due to mutations in the LEPRE1 gene.
www.oif.org/site/PageServer?pagename=AOI_Types - External Health Links
Definition Osteogenesisimperfecta (OI) is a genetic disorder characterized by bones that break easily, often from little or no apparent cause. A classification system of different types of OI is commonly used to help describe how severely a person with OI is affected. For ...
www.oif.org/site/PageServer?pagename=FastFacts - External Health Links
... Size | S S M M L L Bone Basics Osteoporosis OsteogenesisImperfecta Pagets Disease of Bone Related Topics News Glossary ... focus();
Pagets Disease of Bone
www.niams.nih.gov/.../Bone/Osteoporosis/osteoporosis_hoh.asp - External Health Links