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- ... magnesium (Mg2+) to flow into cells; the channel may also allow small amounts of calcium ions (Ca2+) ... signs and symptoms can worsen over time and may lead to early death. More About This Health ...
- ... telomeres. As a result, people with dyskeratosis congenita may experience a variety of problems affecting quickly dividing ... instability of chromosomes resulting from inadequate telomere maintenance may lead to genetic changes that allow cells to ...
- ... in the developing brain. People with Kallmann syndrome may have a poor sense of smell or no ... normal sexual development, and people with this condition may experience puberty later than normal or not at ...
- ... DNA damage can accumulate in cells. Such cells may continue to divide in an uncontrolled way, leading ... multiply uncontrollably to form a tumor. Bladder cancer may cause blood in the urine, pain during urination, ...
- ... suspect that the variants involved in frontometaphyseal dysplasia may change the way the filamin A protein helps ... function." Research suggests that decreased filamin A function may affect the shape of cells in the smooth ...
- ... growths (polyps) at an early age; the polyps may become cancerous.SMAD4 gene mutations that cause this ... TGF-β signaling pathway. Disruption of this pathway may interfere with both the tumor suppressor function of ...
- ... in coordinating cell growth and division, and it may also play a role in controlling the flow of calcium into cells. Studies show it may be important in a process called myelination, which ...
- ... brain, testes, and ovaries. In the brain, it may play a role in the development of connections ... to experience (a characteristic called synaptic plasticity). FMRP may help regulate synaptic plasticity, which is important for ...
- ... inside the nucleus, and researchers believe the proteins may play a role in regulating the activity (expression) ... unclear. Abnormal versions of lamins A and C may alter the activity of certain genes or weaken ...
- ... the increased risk. Researchers speculate that HLA-B27 may abnormally display peptides that trigger an immune reaction, ... that the joint inflammation characteristic of this disorder may result from improper folding of the HLA-B27 ...