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  1. Are chromosomal disorders inherited?: MedlinePlus Genetics 
    ... are not passed from one generation to the next. Some chromosomal conditions are caused by changes in ... cannot be passed from one generation to the next. Learn how to cite this page
    https://medlineplus.gov/.../inheritance/chromosomalinheritance - Genetics
  2. What do geneticists mean by anticipation?: MedlinePlus Genetics 
    ... disorder is passed from one generation to the next. This phenomenon is called anticipation. Anticipation is most ...
    https://medlineplus.gov/.../understanding/inheritance/anticipation - Genetics
  3. What are the different ways a genetic condition can be inherited?: MedlinePlus Genetics 
    Some genetic conditions are caused by variants (also known as mutations) in a single gene. These conditions are usually inherited in one of several patterns, ...
    https://medlineplus.gov/.../inheritance/inheritancepatterns - Genetics
  4. What are whole exome sequencing and whole genome sequencing?: MedlinePlus Genetics 
    ... amounts of DNA. These approaches are known as next-generation sequencing (or next-gen sequencing). The original sequencing technology, called Sanger ... s DNA (known as the person's genome). Next-generation sequencing has sped up the process (taking ...
    https://medlineplus.gov/genetics/understanding/testing/sequencing - Genetics
  5. RB1 gene 
    ... s cells and can be passed to the next generation. The other 60 percent are non-germinal, ... the eye and cannot be passed to the next generation.In germinal retinoblastoma, an RB1 mutation is ...
    https://medlineplus.gov/genetics/gene/rb1 - Genetics
  6. Koolen-de Vries syndrome 
    ... duplicated when the inversion is passed to the next generation. Other, unknown factors are thought to play ... breakpoints of the 17q21.31 microdeletion syndrome with next-generation sequencing. Am J Hum Genet. 2012 Apr ...
    https://medlineplus.gov/genetics/condition/koolen-de-vries-syndrome - Genetics
  7. Retinoblastoma 
    ... passing on the mutated RB1 gene to the next generation. The other two-thirds of retinoblastomas are ... the eye and cannot be passed to the next generation.In hereditary retinoblastoma, mutations in the RB1 ...
    https://medlineplus.gov/genetics/condition/retinoblastoma - Genetics
  8. GLI3 gene 
    ... B), which are characterized by an extra digit next to the little finger or the small toe. ... PPD-IV), which is characterized by extra digits next to the thumb or big toe (hallux) and ...
    https://medlineplus.gov/genetics/gene/gli3 - Genetics
  9. What is a gene variant and how do variants occur?: MedlinePlus Genetics 
    ... variants. These variants cannot be passed to the next generation. Non-inherited variants can be caused by ...
    https://medlineplus.gov/.../mutationsanddisorders/genemutation - Genetics
  10. Wolfram syndrome 
    ... insulin replacement therapy. Optic atrophy is often the next symptom to appear, usually around age 11. The ...
    https://medlineplus.gov/genetics/condition/wolfram-syndrome - Genetics
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