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Paget's Disease of Bone

What is Paget's disease of bone?

Paget's disease of bone is a chronic bone disorder. Normally, there is a process in which your bones break down and then regrow. In Paget's disease, this process is abnormal. There is excessive breakdown and regrowth of bone. Because the bones regrow too quickly, they are bigger and softer than normal. They may be misshapen and easily fractured (broken). Paget's usually affects just one or a few bones.

What causes Paget's disease of bone?

Researchers do not know for sure what causes Paget's disease. Environmental factors may play a role. In some cases, the disease runs in families, and several genes have been linked to the disease.

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Results 1 - 10 of 36 for Osteitis deformans
  1. Paget's Disease of Bone (National Library of Medicine)  
    What is Paget's disease of bone? Paget's disease of bone is a chronic bone disorder. Normally, there is a process in which your bones break down and then regrow. In Paget's disease, ...
  2. ... Philadelphia, PA: Elsevier; 2022:chap 104. Ralston SH. Paget disease of bone. In: Goldman L, Cooney KA, eds. Goldman-Cecil ... Philadelphia, PA: Elsevier; 2024:chap 228. Singer FR. Paget disease of bone. In: Robertson RP, ed. DeGroot's Endocrinology . 8th ed. ...
  3. ClinicalTrials.gov: Osteitis Deformans From the National Institutes of Health (National Institutes of Health)  
    Paget's Disease of Bone/Clinical Trials
  4. ... to cause the disease. Osseous Paget's disease Osteitis deformans Paget disease, bone Paget's disease of bone PDB Genetic Testing Registry: Bone Paget disease Genetic ...
  5. Paget's Disease of Bone (American College of Rheumatology)  
    Paget's Disease of Bone/Start Here
  6. Paget's Disease of Bone From the National Institutes of Health (National Institute of Arthritis and Musculoskeletal and Skin Diseases)  
    Paget's Disease of Bone/Start Here ... Paget's Disease of Bone
  7. Paget's Disease of Bone (American Academy of Orthopaedic Surgeons)  
    Paget's disease of bone is a chronic disease of the skeleton. In healthy bone, a process called remodeling removes old ...
  8. Paget's Disease of Bone: Diagnosis and Treatment (Mayo Foundation for Medical Education and Research)  
    Paget's Disease of Bone/Diagnosis and Tests ... Paget's Disease of Bone ... Mayo Foundation for Medical Education and Research
  9. Paget's Disease of Bone: Symptoms and Causes (Mayo Foundation for Medical Education and Research)  
    Paget's Disease of Bone/Symptoms ... Paget's Disease of Bone ... Mayo Foundation for Medical Education and Research
  10. ... some patients). Alendronate is also used to treat Paget's disease of bone (a condition in which the bones are soft ... in the morning for six months to treat Paget's disease of bone. The effervescent tablets are usually taken on an ...
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